Browsing by Author "Ozen, Filiz"
Now showing items 1-15 of 15
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ANGIOTENSIN CONVERTING ENZYME (ACE) GENE POLYMORPHISM AND BUERGER'S DISEASE
Ozen, Filiz; Kocak, Nadir; Ozdemir, Ozturk; Sezgin, Ilhan (JOHN WILEY & SONS INC, 2009)… -
Association between ABCB1 (MDR1) Gene 3435 C > T Polymorphism and Colchicine Unresponsiveness of FMF Patients
Ozen, Filiz; Silan, Coskun; Uludag, Ahmet; Candan, Ferhan; Silan, Fatma; Ozdemir, Semra; Atik, Sinem; Ozdemir, Ozturk (TAYLOR & FRANCIS LTD, 2011)The multidrug resistance gene-1 (MDR1, adenosine triphosphate-binding cassette transporter: ABCB1, P-glycoprotein) encodes membrane proteins that play a crucial role in protecting cells from xenobiotics, chemicals, and ... -
Association Between ApoE4 Allele and Deep Venous Thrombosis: A Pilot Study
Katrancioglu, Nurkay; Manduz, Sinasi; Ozen, Filiz; Yilmaz, Mehmet Birhan; Atahan, Erhan; Ozdemir, Ozturk; Berkan, Ocal (SAGE PUBLICATIONS INC, 2011)Materials and Methods: We aimed to search the relative frequencies ApoE alleles among patients with DVT and healthy participants. We enrolled 59 consecutive patients with DVT and 59 age- and sex-matched healthy controls. ... -
Clinical and molecular analysis of common MEFV gene mutations in familial Mediterranean fever in Sivas population
Koksal, Binnur; Nur, Naim; Sari, Musa; Candan, Ferhan; Acemoglu, Mursit; Kocak, Nadir; Ozen, Filiz; Ozdemir, Ozturk (SPRINGER, 2009)Familial Mediterranean fever (FMF) is the most frequent hereditary inflammatory disease characterized by self-limited recurrent attacks of fever and serositis. The aim of the current study is to determine the frequency of ... -
Combined Germline Variations of Thrombophilic Genes Promote Genesis of Lung Cancer
Ozen, Filiz; Polat, Fikriye; Arslan, Sulhattin; Ozdemir, Ozturk (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2013)Background: A large variety of familiar and non-familiar lung carcinomas (LC) are caused by long term exposure to chemical carcinogens that are present in tobacco smoke. We aimed to investigate the prevalence of 5 thrombophilic ... -
The CYP4502D6*4 and*6 alleles are the molecular genetic markers for drug response: implications in colchicine non-responder FMF patients
Yalcintepe, Sinem; Ozdemir, Ozturk; Silan, Coskun; Ozen, Filiz; Uludag, Ahmet; Candan, Ferhan; Silan, Fatma (SPRINGER FRANCE, 2016)The cytochrome P450 2D6 (CYP2D6) is a cytochrome P450 enzyme involved in the oxidative biotransformation of the xenobiotics, carcinogens and various clinically important drugs. Patients are evaluated in three sub-groups ... -
Germ-line MTHFR C677T, FV H1299R and PAI-1 5G/4G Variations in Breast Carcinoma
Ozen, Filiz; Erdis, Eda; Sik, Ebru; Silan, Fatma; Uludag, Ahmet; Ozdemir, Ozturk (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2013)Background: Various oncogenes related to cancer have been extensively studied and several polymorphisms have been found to be associated with breast cancer. The current report outlines analysis of germ-line polymorphisms ... -
MEFV mutations and their relation to major clinical symptoms of Familial Mediterranean Fever
Cekin, Nilgun; Akyurek, Murat Eser; Pinarbasi, Ergun; Ozen, Filiz (ELSEVIER SCIENCE BV, 2017)Familial Mediterranean fever is a common hereditary disease in Turkey. To date, different mutational spectrum of MEFV gene was observed in studies carried out in different regions of Turkey but in most of these studies ... -
Methylenetetrahydrofolate Reductase Gene Germ-Line C677T and A1298C SNPs are Associated with Colorectal Cancer Risk in the Turkish Population
Ozen, Filiz; Sen, Metin; Ozdemir, Ozturk (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014)Colorectal cancer (CRC) is the third most common cause of death due to cancer in the worldwide and the incidence is also increasing in Turkey. Our present aim was to investigate any association between germ-line ... -
PREVALENCE OF THE FAMILIAL MEDITERRANEAN FEVER COMMON GENE MUTATIONS IN PATIENTS WITH SIMPLE FEBRILE SEIZURES
Ozen, Filiz; Kocak, Nadir; Kesli, Recep (JOHN WILEY & SONS INC, 2009)… -
A Prospective Case-Control Study Analyzes 12 Thrombophilic Gene Mutations in Turkish Couples with Recurrent Pregnancy Loss
Yenicesu, Gonca Imir; Cetin, Meral; Ozdemir, Ozturk; Cetin, Ali; Ozen, Filiz; Yenicesu, Cem; Yildiz, Caglar; Kocak, Nadir (WILEY, 2010)Problem Recurrent pregnancy loss (RPL) is a heterogeneous disorder. The contribution of specific thrombophilic genes to the pathophysiology of RPL has remained controversial. We evaluated the prevalences of 12 thrombophilic ... -
The Proto-Oncogene KRAS and BRAF Profiles and Some Clinical Characteristics in Colorectal Cancer in the Turkish Population
Ozen, Filiz; Ozdemir, Semra; Zemheri, Ebru; Hacimuto, Gizem; Silan, Fatma; Ozdemir, Ozturk (MARY ANN LIEBERT INC, 2013)Objectives: The aim of the current study was to investigate the prevalence and predictive significance of the KRAS and BRAF mutations in Turkish patients with colorectal cancer (CRC). Methods: Totally, 53 fresh tumoral ... -
Recurrent Pregnancy Loss and Its Relation to Combined Parental Thrombophilic Gene Mutations
Ozdemir, Ozturk; Yenicesu, Gonca Imir; Silan, Fatma; Koksal, Binnur; Atik, Sinem; Ozen, Filiz; Gol, Mert; Cetin, Ali (MARY ANN LIEBERT, INC, 2012)Background and Aim: Recurrent pregnancy loss (RPL) is a heterogeneous disorder that has been associated with antiphospholipid syndrome and other prothrombotic parameters. We aimed to investigate the prevalence of 12 ...